Across TCGA patient cohorts, PTP4A2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,063 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PTP4A2-associated genes across cancer lineages are UTP4, GARS1, and EIF3B. Each is linked with PTP4A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PTP4A2-to-partner and partner-to-PTP4A2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A2→partner) and Y-score (partner→PTP4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTP4 →	-0.520	-0.254	<.001	<.001	3	5
BRCA	GARS1 →	-0.624	-0.401	<.001	.001	3	4
BRCA	EIF3B →	-0.522	-0.491	<.001	<.001	3	4
LSCC	PPIF →	-0.769	-0.359	<.001	<.001	3	4
BRCA	CDCA3 →	-0.838	-0.422	<.001	<.001	3	4
BRCA	DDX39A →	-0.570	-0.498	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,063 associations by consensus.

Exploration

PTP4A2 survival (RNA) · tumor vs normal (RNA) · all PTP4A2 data types