Across TCGA patient cohorts, PTP4A2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTP4A2-associated genes across cancer lineages are MPP, CD8+ naive T-cells, and Endothelial cells. Each is linked with PTP4A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTP4A2-to-partner and partner-to-PTP4A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A2→partner) and Y-score (partner→PTP4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MPP →	+0.034	+3.609	.003	.014	3	1
UCEC	CD8+ naive T-cells →	+0.043	+2.364	.001	.019	1	1
UCEC	Endothelial cells →	-0.039	-2.279	.041	.036	1	1
UCEC	lymphatic Endothelial cells →	-0.027	-3.405	.023	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

PTP4A2 survival (RNA) · tumor vs normal (RNA) · all PTP4A2 data types