PTOV1-AS2

Across TCGA pan-cancer cohorts, PTOV1-AS2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PTOV1-AS2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PTOV1-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PTOV1-AS2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, KIRC, and PAAD are the cancer types where PTOV1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.722	0.599	<.001	103	view →
KIRC	DFS	Median	All	0.494	0.709	<.001	99	view →
PAAD	OS	Median	All	0.508	0.266	<.001	84	view →
ACC	DFS	Median	All	0.420	0.745	<.001	84	view →
BLCA	OS	Median	All	0.770	0.647	.001	76	view →
LGG	DFS	Median	All	0.628	0.840	<.001	51	view →
MESO	OS	Median	All	0.291	0.468	.005	47	view →
SKCM	OS	Median	All	0.395	0.250	.002	40	view →
COAD	OS	Quartile	All	0.707	0.908	.003	37	view →
PRAD	DFS	Tertile	All	0.729	0.946	<.001	26	view →
LIHC	DFS	Median	All	0.390	0.477	.011	20	view →
UVM	OS	Median	III,IV	0.304	1.000	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PTOV1-AS2–HNSC (OS)

Open the HNSC breakdown →