PTOV1-AS2

Across TCGA pan-cancer cohorts, PTOV1-AS2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of PTOV1-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PTOV1-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PTOV1-AS2 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, HNSC, and STAD are the cancer types where PTOV1-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PTOV1-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.507	<.001	10	view →
HNSC	All	All	+0.477	<.001	10	view →
STAD	All	II,III,IV	+0.843	<.001	8	view →
KIRC	Male	II,III,IV	+0.547	<.001	8	view →
LIHC	All	II,III,IV	+0.793	<.001	7	view →
BLCA	All	All	+0.801	.004	6	view →
UCEC	All	All	+0.724	.001	6	view →
CHOL	Male	All	+2.125	<.001	5	view →
READ	All	All	+1.185	<.001	2	view →
ESCA	All	All	+0.991	.016	2	view →
PRAD	All	All	+0.389	.006	2	view →
KIRC	Female	IV	−0.436	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

PTOV1-AS2–COAD

Open the COAD breakdown →