PTN

Across TCGA patient cohorts, PTN RNA expression is significantly associated with the protein abundance of many other proteins, with 15,700 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTN-associated proteins across cancer lineages are FERMT2, SORBS3, and KANK2. Each is linked with PTN in more than 6 cancer types. Because this analysis shows association rather than direction, both PTN-to-partner and partner-to-PTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTN versus FERMT2 in COAD, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTN→partner) and Y-score (partner→PTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FERMT2 →	+0.630	+0.818	<.001	<.001	3	7
UCEC	SORBS3 →	+0.679	+1.722	<.001	<.001	3	6
UCEC	KANK2 →	+0.587	+1.571	.001	<.001	3	6
COAD	PGM5 →	+0.890	+0.813	<.001	<.001	3	6
BRCA	TLN2 →	+0.470	+1.125	<.001	<.001	3	6
UCEC	TNS1 →	+0.732	+1.657	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,700 associations by consensus.

PTN vs FERMT2 — COAD

Explore this scatter interactively →