PTMAP11

Across TCGA patient cohorts, PTMAP11 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTMAP11-associated genes across cancer lineages are RNU6-879P, DEFA7P, and SNORA24B. Each is linked with PTMAP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTMAP11-to-partner and partner-to-PTMAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-879P grouped by PTMAP11-low versus PTMAP11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTMAP11→partner) and Y-score (partner→PTMAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-879P →	+0.556	+2.996	.006	.009	3	1
UCEC	DEFA7P →	+0.227	+4.132	<.001	.009	3	1
UCEC	SNORA24B →	+0.701	+3.676	<.001	.001	3	1
UCEC	RNU6-905P →	+0.383	+5.148	<.001	.002	3	1
UCEC	RNU6-939P →	+0.301	+4.923	<.001	.002	3	1
UCEC	MIR596 →	+0.831	+3.639	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RNU6-879P by PTMAP11 expression — UCEC

Explore this box plot interactively →