Q-omics provides the consensus-scored DEFA7P profile across patient tissues and cancer cell-line models. DEFA7P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, DEFA7P RNA expression shows 5,958 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BLCA, and STAD as cancer lineages where DEFA7P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFA7P survival associations across molecular data types. DEFA7P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFA7P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	BLCA (135)	view →

This table ranks reproducible DEFA7P RNA expression–survival associations across cancer types. High DEFA7P expression shows unfavorable associations in BLCA, READ, SKCM, OV, DLBC and COAD. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for DEFA7P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.089	0.551	<.001	135	view →
READ	DFS	Tertile	All	0.082	0.799	<.001	69	view →
SKCM	OS	Tertile	All	0.253	0.784	<.001	54	view →
OV	OS	Tertile	IV	0.059	0.759	.006	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
COAD	DFS	Tertile	III,IV	0.167	0.667	.029	18	view →

Pink = unfavorable, green = favorable. all 12 lineages →

DEFA7P-BLCA (DFS)

Kaplan–Meier survival curve for DEFA7P RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFA7P in patient tissues and cancer cell lines. In patient samples, DEFA7P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,958	STAD (5851)	view →
RNA	3,053	ESCA (1037)	view →