Across TCGA patient cohorts, PTMA protein abundance is significantly associated with the RNA expression of many other genes, with 10,139 significant associations in total. OV shows the largest number of these associations.

The most reproducible PTMA-associated genes across cancer lineages are NCL, USP37, and CNOT9. Each is linked with PTMA in more than 6 cancer types. Because this analysis shows association rather than direction, both PTMA-to-partner and partner-to-PTMA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTMA→partner) and Y-score (partner→PTMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NCL →	+0.695	+0.338	<.001	<.001	3	7
BRCA	USP37 →	+0.694	+0.557	<.001	<.001	3	7
UCEC	CNOT9 →	+0.482	+0.299	<.001	<.001	3	7
HNSC	STMN1 →	+1.023	+0.433	<.001	<.001	3	6
GBM	HELLS →	+0.907	+0.508	<.001	<.001	3	6
UCEC	BARD1 →	+0.638	+0.281	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,139 associations by consensus.

Exploration

PTMA survival (RNA) · tumor vs normal (RNA) · all PTMA data types