PTK7

Across TCGA patient cohorts, PTK7 protein abundance is significantly associated with the RNA expression of many other genes, with 15,121 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTK7-associated genes across cancer lineages are NXN, TGFB1I1, and MFAP2. Each is linked with PTK7 in more than 8 cancer types. Because this analysis shows association rather than direction, both PTK7-to-partner and partner-to-PTK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTK7 versus NXN in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTK7→partner) and Y-score (partner→PTK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NXN →	+1.073	+0.466	<.001	<.001	3	9
OV	TGFB1I1 →	+1.060	+0.381	<.001	<.001	3	9
OV	MFAP2 →	+1.650	+0.428	<.001	<.001	3	8
UCEC	PRICKLE1 →	+0.756	+0.257	<.001	.004	3	8
COAD	DACT1 →	+1.107	+0.564	<.001	<.001	3	8
LSCC	CASC15 →	+1.107	+0.458	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,121 associations by consensus.

PTK7 vs NXN — BRCA

Explore this scatter interactively →