PTK2B

Across TCGA patient cohorts, PTK2B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,378 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTK2B-associated proteins across cancer lineages are ITGAL, CORO1A, and DOCK8. Each is linked with PTK2B in more than 9 cancer types. Because this analysis shows association rather than direction, both PTK2B-to-partner and partner-to-PTK2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTK2B versus ITGAL in BRCA, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTK2B→partner) and Y-score (partner→PTK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ITGAL →	+0.610	+0.535	<.001	<.001	3	10
UCEC	CORO1A →	+0.602	+0.796	<.001	<.001	3	9
UCEC	DOCK8 →	+0.491	+0.722	.002	.001	3	9
UCEC	LCP1 →	+0.612	+0.736	<.001	.002	3	9
GBM	PSMB10 →	+0.469	+0.748	.001	<.001	3	8
GBM	PTPN6 →	+0.547	+0.841	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,378 associations by consensus.

PTK2B vs ITGAL — BRCA

Explore this scatter interactively →