PTK2B

Across TCGA patient cohorts, PTK2B protein abundance is significantly associated with the RNA expression of many other genes, with 17,927 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTK2B-associated genes across cancer lineages are CD48, CD7, and NCR3. Each is linked with PTK2B in more than 8 cancer types. Because this analysis shows association rather than direction, both PTK2B-to-partner and partner-to-PTK2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTK2B versus CD48 in OV, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTK2B→partner) and Y-score (partner→PTK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD48 →	+0.996	+0.378	<.001	<.001	3	9
BRCA	CD7 →	+1.145	+0.364	<.001	<.001	3	9
BRCA	NCR3 →	+0.613	+0.348	<.001	<.001	3	9
HNSC	LINC01871 →	+1.127	+0.260	<.001	<.001	3	9
BRCA	TBX21 →	+0.842	+0.351	<.001	<.001	3	9
OV	PLEK →	+1.279	+0.464	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,927 associations by consensus.

PTK2B vs CD48 — OV

Explore this scatter interactively →