PTK2B

Across TCGA patient cohorts, PTK2B protein abundance is significantly associated with the protein abundance of many other proteins, with 24,961 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTK2B-associated proteins across cancer lineages are CORO1A, CYBB, and FMNL1. Each is linked with PTK2B in more than 9 cancer types. Because this analysis shows association rather than direction, both PTK2B-to-partner and partner-to-PTK2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTK2B versus CORO1A in OV, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTK2B→partner) and Y-score (partner→PTK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CORO1A →	+0.671	+0.526	<.001	<.001	3	10
BRCA	CYBB →	+0.883	+0.384	<.001	<.001	3	10
UCEC	FMNL1 →	+0.642	+0.453	<.001	<.001	3	10
BRCA	FNBP1 →	+0.408	+0.373	<.001	<.001	3	10
GBM	AMPD3 →	+0.518	+0.479	.002	<.001	3	10
BRCA	CARD16 →	+0.570	+0.387	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,961 associations by consensus.

PTK2B vs CORO1A — OV

Explore this scatter interactively →