PTH1R

Across TCGA patient cohorts, PTH1R RNA expression is significantly associated with the protein abundance of many other proteins, with 22,852 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTH1R-associated proteins across cancer lineages are SEPTIN11, HSPA12B, and KANK2. Each is linked with PTH1R in more than 9 cancer types. Because this analysis shows association rather than direction, both PTH1R-to-partner and partner-to-PTH1R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTH1R versus SEPTIN11 in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTH1R→partner) and Y-score (partner→PTH1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN11 →	+0.469	+0.860	<.001	<.001	3	10
BRCA	HSPA12B →	+0.635	+0.900	<.001	<.001	3	10
BRCA	KANK2 →	+0.677	+1.033	<.001	<.001	3	10
BRCA	TNS2 →	+0.397	+0.734	<.001	<.001	3	10
OV	TNS2_S120 →	+0.632	+0.998	<.001	<.001	3	10
UCEC	TPM1 →	+0.663	+0.769	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,852 associations by consensus.

PTH1R vs SEPTIN11 — BRCA

Explore this scatter interactively →