PTH1R

Across TCGA cell cohorts, PTH1R RNA expression is significantly associated with the go_rna of many other GO terms, with 1,734 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PTH1R-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions, Regulation of respiratory gaseous exchange by nervous system process, and Cytoplasmic translation. Each is linked with PTH1R in more than 7 cancer types. Because this analysis shows association rather than direction, both PTH1R-to-partner and partner-to-PTH1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions grouped by PTH1R-low versus PTH1R-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTH1R→partner) and Y-score (partner→PTH1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.053	+0.839	<.001	<.001	3	8
OESOPHAGUS	Regulation of respiratory gaseous exchange by nervous system process →	+1.013	+0.470	<.001	.007	3	7
BLOOD_Lymphoma	Cytoplasmic translation →	+0.053	+0.222	<.001	<.001	3	7
OESOPHAGUS	Export across plasma membrane →	-0.118	-0.458	<.001	.008	3	6
LARGE_INTESTINE	Potassium ion import across plasma membrane →	-0.194	-0.551	<.001	<.001	3	6
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.074	+0.159	<.001	.002	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,734 associations by consensus.

RNA splicing, via transesterification reactions by PTH1R expression — SOFT_TISSUE

Explore this box plot interactively →