PTGS1

Across TCGA patient cohorts, PTGS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,351 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTGS1-associated proteins across cancer lineages are DAB2, MAP4, and LRP1. Each is linked with PTGS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTGS1-to-partner and partner-to-PTGS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGS1 versus DAB2 in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGS1→partner) and Y-score (partner→PTGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DAB2 →	+0.378	+0.754	<.001	<.001	3	6
LSCC	MAP4 →	+0.302	+0.820	<.001	<.001	3	6
BRCA	LRP1 →	+0.532	+0.765	<.001	<.001	3	6
COAD	ZYX →	+0.429	+0.784	<.001	<.001	3	5
COAD	RAI14 →	+0.399	+0.683	<.001	<.001	3	5
COAD	NNMT →	+0.645	+0.578	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,351 associations by consensus.

PTGS1 vs DAB2 — LSCC

Explore this scatter interactively →