PTGR1

Across TCGA patient cohorts, PTGR1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,532 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PTGR1-associated genes across cancer lineages are TMEM245, HDHD3, and ALAD. Each is linked with PTGR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTGR1-to-partner and partner-to-PTGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGR1 versus TMEM245 in LUAD, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGR1→partner) and Y-score (partner→PTGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TMEM245 →	+0.559	+0.642	<.001	<.001	3	6
HNSC	HDHD3 →	+0.805	+0.694	<.001	<.001	3	6
BRCA	ALAD →	+0.603	+0.598	<.001	<.001	3	6
HNSC	CES1 →	+2.913	+0.707	<.001	<.001	3	5
LSCC	TXN →	+1.332	+1.162	<.001	<.001	3	5
BRCA	IDNK →	+0.964	+0.644	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,532 associations by consensus.

PTGR1 vs TMEM245 — LUAD

Explore this scatter interactively →