PTGES3P5

Across TCGA patient cohorts, PTGES3P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,756 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PTGES3P5-associated GO terms across cancer lineages are Regulation of protein binding, Vesicle-mediated transport in synapse, and Regulation of cell junction assembly. Each is linked with PTGES3P5 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTGES3P5-to-partner and partner-to-PTGES3P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein binding grouped by PTGES3P5-low versus PTGES3P5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES3P5→partner) and Y-score (partner→PTGES3P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein binding →	+0.154	+0.026	<.001	.007	3	5
STAD	Vesicle-mediated transport in synapse →	+0.097	+0.047	<.001	.001	2	6
LIHC	Regulation of cell junction assembly →	+0.029	+0.010	<.001	.003	3	4
STAD	DNA-templated transcription initiation →	+0.164	+0.037	<.001	.004	3	4
STAD	Transcription initiation at RNA polymerase II promoter →	+0.160	+0.030	<.001	.001	3	4
STAD	Negative regulation of protein catabolic process →	+0.159	+0.027	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,756 associations by consensus.

Regulation of protein binding by PTGES3P5 expression — STAD

Explore this box plot interactively →