PTGES3P4

Across TCGA patient cohorts, PTGES3P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,916 significant associations in total. OV shows the largest number of these associations.

The most reproducible PTGES3P4-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Regulation of microtubule-based process, and DNA biosynthetic process. Each is linked with PTGES3P4 in more than 27 cancer types. Because this analysis shows association rather than direction, both PTGES3P4-to-partner and partner-to-PTGES3P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by PTGES3P4-low versus PTGES3P4-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES3P4→partner) and Y-score (partner→PTGES3P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of chromosome organization →	+0.084	+0.521	.001	<.001	2	28
ESCA	Regulation of microtubule-based process →	+0.052	+0.402	.002	<.001	3	27
DLBC	DNA biosynthetic process →	+0.080	+0.514	<.001	<.001	2	28
DLBC	Protein localization to cytoskeleton →	+0.068	+0.545	.002	<.001	2	27
DLBC	Positive regulation of mRNA metabolic process →	+0.066	+0.724	.001	<.001	2	27
DLBC	Mitotic sister chromatid cohesion →	+0.100	+0.525	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,916 associations by consensus.

Positive regulation of chromosome organization by PTGES3P4 expression — DLBC

Explore this box plot interactively →