PTGES3P4

Across TCGA pan-cancer cohorts, PTGES3P4 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PTGES3P4 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher PTGES3P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PTGES3P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CHOL show a favorable association.

SKCM, CHOL, and LUAD are the cancer types where PTGES3P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	III,IV	0.843	0.750	.003	53	view →
CHOL	DFS	Median	II,III,IV	0.701	0.129	.010	39	view →
LUAD	OS	Tertile	III,IV	0.360	0.691	.011	35	view →
ACC	DFS	Median	II,III,IV	0.292	0.712	.001	32	view →
UCS	DFS	Quartile	III,IV	0.565	0.113	.010	30	view →
BRCA	DFS	Quartile	All	0.413	0.574	<.001	27	view →
KIRC	DFS	Tertile	II,III,IV	0.396	0.599	.022	22	view →
READ	DFS	Tertile	All	1.000	0.456	.005	14	view →
LIHC	OS	Tertile	II,III,IV	0.659	0.352	.009	12	view →
LGG	OS	Tertile	All	0.941	0.848	<.001	10	view →
KIRP	DFS	Quartile	IV	0.687	0.047	.024	6	view →
LUSC	OS	Quartile	All	0.641	0.302	.002	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PTGES3P4–SKCM (OS)

Open the SKCM breakdown →