PTGES3L

Across TCGA cell cohorts, PTGES3L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,506 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PTGES3L-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Establishment of protein localization to organelle. Each is linked with PTGES3L in more than 7 cancer types. Because this analysis shows association rather than direction, both PTGES3L-to-partner and partner-to-PTGES3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by PTGES3L-low versus PTGES3L-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES3L→partner) and Y-score (partner→PTGES3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.103	+0.698	<.001	.001	3	8
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.100	+0.698	<.001	.001	3	8
OESOPHAGUS	Establishment of protein localization to organelle →	+0.045	+0.753	.004	.008	3	8
BLOOD_Leukemia	Formation of cytoplasmic translation initiation complex →	+0.064	+1.109	.001	<.001	3	8
SOFT_TISSUE	Nucleic acid transport →	+0.080	+1.958	.002	<.001	3	7
SOFT_TISSUE	RNA transport →	+0.080	+1.958	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,506 associations by consensus.

Negative regulation of myoblast fusion by PTGES3L expression — BLOOD_Lymphoma

Explore this box plot interactively →