PTGES3L

Across TCGA cell cohorts, PTGES3L mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PTGES3L-associated genes across cancer lineages are OOSP2 and FCAR. Each is linked with PTGES3L in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGES3L-to-partner and partner-to-PTGES3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP2 grouped by PTGES3L-low versus PTGES3L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES3L→partner) and Y-score (partner→PTGES3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OOSP2 →	+0.011	+4.562	<.001	<.001	3	1
CNS	FCAR →	+0.059	+4.472	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OOSP2 by PTGES3L expression — LARGE_INTESTINE

Explore this box plot interactively →