PTGES3L-AARSD1

Across TCGA patient cohorts, PTGES3L-AARSD1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,794 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PTGES3L-AARSD1-associated genes across cancer lineages are CCDC134, CHADL, and ALG13. Each is linked with PTGES3L-AARSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGES3L-AARSD1-to-partner and partner-to-PTGES3L-AARSD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGES3L-AARSD1 versus CCDC134 in HNSC, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES3L-AARSD1→partner) and Y-score (partner→PTGES3L-AARSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCDC134 →	-0.858	-1.315	.001	.005	3	1
HNSC	CHADL →	-0.778	-1.248	.001	.002	3	1
HNSC	ALG13 →	+0.707	+1.032	.002	<.001	3	1
HNSC	BPNT2 →	+0.810	+1.039	.003	<.001	3	1
HNSC	HSD17B1 →	-1.041	-0.959	.003	.008	3	1
HNSC	TRPV4 →	-2.103	-1.136	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,794 associations by consensus.

PTGES3L-AARSD1 vs CCDC134 — HNSC

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