PTGES3L-AARSD1

Across TCGA patient cohorts, PTGES3L-AARSD1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTGES3L-AARSD1-associated genes across cancer lineages are Adipocytes, Th2 cells, and Myocytes. Each is linked with PTGES3L-AARSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGES3L-AARSD1-to-partner and partner-to-PTGES3L-AARSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by PTGES3L-AARSD1-low versus PTGES3L-AARSD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES3L-AARSD1→partner) and Y-score (partner→PTGES3L-AARSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.020	+2.092	.009	.013	3	2
UCEC	Th2 cells →	+0.239	+2.807	.002	.003	2	2
SKCM	Myocytes →	+0.068	+3.031	.001	.019	1	2
SKCM	Neurons →	+0.024	+3.019	.026	.019	2	1
UCEC	Class-switched memory B-cells →	-0.062	-3.906	.012	<.001	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Adipocytes by PTGES3L-AARSD1 expression — UCEC

Explore this box plot interactively →