PTGES

Across TCGA patient cohorts, PTGES RNA expression is significantly associated with the protein abundance of many other proteins, with 15,017 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTGES-associated proteins across cancer lineages are SLC16A3, CEBPB, and ECM1. Each is linked with PTGES in more than 4 cancer types. Because this analysis shows association rather than direction, both PTGES-to-partner and partner-to-PTGES results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGES versus SLC16A3 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES→partner) and Y-score (partner→PTGES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A3 →	+0.554	+0.701	<.001	<.001	3	5
CCRCC	CEBPB →	+0.381	+1.114	<.001	<.001	3	5
PDAC	ECM1 →	+0.560	+0.897	<.001	<.001	3	5
GBM	S100A11_S6 →	+0.694	+0.756	<.001	<.001	3	4
BRCA	H1-0 →	+0.738	+1.443	<.001	<.001	3	4
GBM	ITGA3 →	+0.628	+0.925	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,017 associations by consensus.

PTGES vs SLC16A3 — GBM

Explore this scatter interactively →