PTGER3

Across TCGA cell cohorts, PTGER3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,737 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PTGER3-associated GO terms across cancer lineages are RNA catabolic process, Establishment of protein localization to organelle, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with PTGER3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PTGER3-to-partner and partner-to-PTGER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA catabolic process grouped by PTGER3-low versus PTGER3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGER3→partner) and Y-score (partner→PTGER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA catabolic process →	+0.072	+3.743	<.001	<.001	3	7
BLOOD_Leukemia	Establishment of protein localization to organelle →	+0.026	+1.177	<.001	<.001	3	7
BLOOD_Leukemia	Regulation of ubiquitin-dependent protein catabolic process →	+0.033	+1.242	<.001	<.001	3	6
SKIN	Post-translational protein targeting to membrane, translocation →	+0.079	+0.225	<.001	.006	3	6
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.097	+0.303	<.001	.001	3	6
BLOOD_Lymphoma	Excitatory postsynaptic potential →	-0.097	-0.981	<.001	.002	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,737 associations by consensus.

RNA catabolic process by PTGER3 expression — BONE

Explore this box plot interactively →