PTGER3

Across TCGA pan-cancer cohorts, PTGER3 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PTGER3 data layer compared with 9 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PTGER3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PTGER3 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

KIRC, KIRP, and BRCA are the cancer types where PTGER3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.718	0.500	<.001	114	view →
KIRP	DFS	Median	All	0.792	0.922	<.001	106	view →
BRCA	OS	Median	All	0.950	0.895	<.001	93	view →
BLCA	OS	Tertile	All	0.327	0.621	<.001	80	view →
OV	DFS	Median	All	0.497	0.584	.005	52	view →
CHOL	OS	Median	All	0.827	0.385	<.001	42	view →
LGG	DFS	Median	All	0.894	0.768	<.001	41	view →
ACC	OS	Tertile	All	0.865	0.334	.002	25	view →
UVM	OS	Median	II,III,IV	0.764	0.924	.011	20	view →
SARC	OS	Tertile	All	0.821	0.656	.002	17	view →
THCA	OS	Quartile	All	0.969	1.000	.013	16	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PTGER3–KIRC (DFS)

Open the KIRC breakdown →