PTGDR2

Across TCGA patient cohorts, PTGDR2 mutation is significantly associated with the RNA expression of many other genes, with 298 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PTGDR2-associated genes across cancer lineages are RN7SKP44, RNU6-393P, and SNORD56B. Each is linked with PTGDR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGDR2-to-partner and partner-to-PTGDR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP44 grouped by PTGDR2-low versus PTGDR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGDR2→partner) and Y-score (partner→PTGDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP44 →	+0.339	+5.435	<.001	.005	3	2
COAD	RNU6-393P →	+1.256	+6.917	<.001	<.001	3	2
COAD	SNORD56B →	+3.166	+5.693	<.001	.003	3	2
COAD	MIR620 →	+0.862	+6.917	<.001	<.001	3	2
COAD	RNA5SP104 →	+2.045	+5.790	<.001	.003	3	2
UCEC	LINC02104 →	+0.339	+3.468	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 298 associations by consensus.

RN7SKP44 by PTGDR2 expression — COAD

Explore this box plot interactively →