PTCHD1-AS

Across TCGA pan-cancer cohorts, PTCHD1-AS RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PTCHD1-AS data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PTCHD1-AS RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PTCHD1-AS expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UCS, and LGG are the cancer types where PTCHD1-AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.457	0.238	.003	53	view →
UCS	OS	Tertile	II,III,IV	0.565	0.206	.020	52	view →
LGG	OS	Median	All	0.716	0.902	<.001	51	view →
ESCA	DFS	Quartile	III,IV	0.659	0.253	.007	32	view →
UVM	DFS	Tertile	II,III,IV	0.530	0.784	.035	24	view →
COAD	OS	Tertile	IV	0.242	0.683	.008	24	view →
UCEC	DFS	Quartile	II,III,IV	0.774	0.851	.016	24	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
KICH	DFS	Tertile	All	0.724	0.917	.034	15	view →
LUAD	OS	Median	II,III,IV	0.357	0.175	.010	15	view →
DLBC	OS	Median	II,III,IV	0.359	1.000	.010	14	view →
SKCM	OS	Quartile	IV	1.000	0.293	.029	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PTCHD1-AS–HNSC (DFS)

Open the HNSC breakdown →