PTCD1

Across TCGA cell cohorts, PTCD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,290 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PTCD1-associated genes across cancer lineages are AP4M1, SLC12A9, and POLR2J. Each is linked with PTCD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PTCD1-to-partner and partner-to-PTCD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCD1 versus AP4M1 in KIDNEY, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD1→partner) and Y-score (partner→PTCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	AP4M1 →	+1.164	+0.937	.006	.004	3	5
OESOPHAGUS	SLC12A9 →	+0.833	+0.879	<.001	<.001	3	4
OESOPHAGUS	POLR2J →	+0.938	+0.924	.007	.002	2	5
STOMACH	KCTD13 →	+0.910	+0.848	.005	.004	3	4
LUNG_NSCLC_LUSC	SPDYE16 →	+0.120	+1.290	.006	.006	3	4
LUNG_NSCLC_LUSC	ERLEC1 →	-1.012	-1.374	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,290 associations by consensus.

PTCD1 vs AP4M1 — KIDNEY

Explore this scatter interactively →