PSTK

Across TCGA patient cohorts, PSTK RNA expression is significantly associated with the RNA expression of many other genes, with 20,191 significant associations in total. UVM shows the largest number of these associations.

The most reproducible PSTK-associated genes across cancer lineages are C10orf88, TIAL1, and NSMCE4A. Each is linked with PSTK in more than 33 cancer types. Because this analysis shows association rather than direction, both PSTK-to-partner and partner-to-PSTK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSTK versus C10orf88 in UVM, with a Pearson correlation of 0.90.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSTK→partner) and Y-score (partner→PSTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	C10orf88 →	+1.056	+1.074	<.001	<.001	3	34
UVM	TIAL1 →	+1.397	+1.074	<.001	<.001	3	32
SCLC	NSMCE4A →	+4.308	+0.593	<.001	<.001	3	32
UVM	EEF1AKMT2 →	+1.082	+0.992	<.001	<.001	3	31
UVM	DCLRE1A →	+1.381	+1.092	<.001	<.001	3	31
UVM	BBIP1 →	+1.171	+1.125	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,191 associations by consensus.

PSTK vs C10orf88 — UVM

Explore this scatter interactively →