PSPN

Across TCGA cell cohorts, PSPN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,483 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PSPN-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Lipoprotein localization. Each is linked with PSPN in more than 10 cancer types. Because this analysis shows association rather than direction, both PSPN-to-partner and partner-to-PSPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by PSPN-low versus PSPN-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSPN→partner) and Y-score (partner→PSPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.078	+0.568	.006	.001	3	11
STOMACH	Electron transport coupled proton transport →	+0.078	+0.568	.006	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Lipoprotein localization →	+0.146	+0.359	<.001	.001	3	11
PANCREAS	Negative regulation of protein localization to chromatin →	+0.118	+0.403	.002	<.001	3	10
BONE	RNA catabolic process →	+0.060	+0.402	<.001	.005	3	10
LUNG_SCLC	DNA repair-dependent chromatin remodeling →	+0.077	+0.368	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,483 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by PSPN expression — STOMACH

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