Across TCGA pan-cancer cohorts, PSMG4 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PSMG4 data layer compared with 21 for mass-spec protein and 7 for mass-spec protein.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher PSMG4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PSMG4 expression acts as an unfavorable survival marker.
LIHC are the cancer types where PSMG4 Mutation most reproducibly stratifies survival.