PSMG4

Across TCGA patient cohorts, PSMG4 protein abundance is significantly associated with the RNA expression of many other genes, with 3,653 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PSMG4-associated genes across cancer lineages are E2F3, ACKR3, and PTMS. Each is linked with PSMG4 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSMG4-to-partner and partner-to-PSMG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMG4 versus E2F3 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMG4→partner) and Y-score (partner→PSMG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	E2F3 →	+0.618	+0.226	<.001	<.001	3	3
LSCC	ACKR3 →	-1.111	-0.237	.004	.002	3	3
OV	PTMS →	-0.674	-0.534	.003	.001	3	2
OV	NKX6-1 →	-1.101	-0.456	.005	.008	3	2
OV	SALL2 →	-1.006	-0.509	.001	.004	3	2
BRCA	CTSF →	-0.697	-0.256	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

PSMG4 vs E2F3 — BRCA

Explore this scatter interactively →