PSMG4

Across TCGA patient cohorts, PSMG4 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMG4-associated genes across cancer lineages are RNA5SP198, RN7SL714P, and MIR6792. Each is linked with PSMG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMG4-to-partner and partner-to-PSMG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by PSMG4-low versus PSMG4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMG4→partner) and Y-score (partner→PSMG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP198 →	+0.712	+3.399	<.001	.005	3	2
UCEC	RN7SL714P →	+0.158	+3.630	<.001	.003	3	2
UCEC	MIR6792 →	+0.624	+3.077	<.001	.001	3	1
UCEC	MIR7976 →	+0.466	+2.868	.001	.006	3	1
UCEC	MIR4672 →	+0.609	+3.211	<.001	<.001	3	1
UCEC	RN7SL262P →	+0.377	+2.803	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

RNA5SP198 by PSMG4 expression — UCEC

Explore this box plot interactively →