PSMG4

Across TCGA cell cohorts, PSMG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,751 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PSMG4-associated GO terms across cancer lineages are Proteasome core complex assembly, Proteasome assembly, and Ubiquinone biosynthetic process. Each is linked with PSMG4 in more than 19 cancer types. Because this analysis shows association rather than direction, both PSMG4-to-partner and partner-to-PSMG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome core complex assembly grouped by PSMG4-low versus PSMG4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMG4→partner) and Y-score (partner→PSMG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Proteasome core complex assembly →	+0.185	+1.357	<.001	<.001	3	20
URINARY_TRACT	Proteasome assembly →	+0.109	+1.190	<.001	<.001	3	14
OESOPHAGUS	Ubiquinone biosynthetic process →	+0.059	+0.576	.005	.006	3	9
PANCREAS	[4Fe-4S] cluster assembly →	+0.141	+1.053	.001	.001	3	9
OESOPHAGUS	Quinone biosynthetic process →	+0.059	+0.576	.005	.006	3	9
SOFT_TISSUE	Radial glial cell differentiation →	-0.146	-0.779	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,751 associations by consensus.

Proteasome core complex assembly by PSMG4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →