PSMG3-AS1

Across TCGA pan-cancer cohorts, PSMG3-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PSMG3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PSMG3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PSMG3-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

KIRC, PAAD, and THCA are the cancer types where PSMG3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.706	0.537	<.001	56	view →
PAAD	OS	Median	All	0.504	0.287	<.001	37	view →
THCA	OS	Quartile	All	0.688	0.922	.004	26	view →
PCPG	DFS	Quartile	All	1.000	0.765	<.001	19	view →
MESO	DFS	Tertile	All	0.239	0.688	.019	18	view →
HNSC	DFS	Median	III,IV	0.668	0.515	.002	11	view →
READ	DFS	Median	IV	0.179	0.936	.010	10	view →
UCEC	DFS	Median	All	0.714	0.590	.008	10	view →
LGG	OS	Tertile	All	0.733	0.850	.002	10	view →
COAD	OS	Median	IV	0.872	0.425	.013	9	view →
CHOL	OS	Tertile	II,III,IV	0.969	0.463	.040	9	view →
GBM	DFS	Quartile	All	0.209	0.357	.021	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PSMG3-AS1–KIRC (DFS)

Open the KIRC breakdown →