PSME2

Across TCGA patient cohorts, PSME2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSME2-associated genes across cancer lineages are ETV7, IRF1, and APOL3. Each is linked with PSME2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PSME2-to-partner and partner-to-PSME2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSME2 versus ETV7 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSME2→partner) and Y-score (partner→PSME2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ETV7 →	+1.483	+0.530	<.001	<.001	3	10
HNSC	IRF1 →	+1.253	+0.489	<.001	<.001	3	10
HNSC	APOL3 →	+1.507	+0.486	<.001	<.001	3	10
HNSC	IDO1 →	+2.057	+0.470	<.001	<.001	3	10
HNSC	PARP9 →	+0.915	+0.364	<.001	<.001	3	10
HNSC	WARS1 →	+1.610	+0.490	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,284 associations by consensus.

PSME2 vs ETV7 — OV

Explore this scatter interactively →