PSMD9

Across TCGA patient cohorts, PSMD9 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD9-associated genes across cancer lineages are UBC, UBXN6, and OR2L2. Each is linked with PSMD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD9-to-partner and partner-to-PSMD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBC grouped by PSMD9-low versus PSMD9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD9→partner) and Y-score (partner→PSMD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBC →	+0.574	+3.201	.002	.009	3	1
UCEC	UBXN6 →	+0.472	+3.217	.009	.009	3	1
COAD	OR2L2 →	+0.156	+5.602	.005	.004	3	1
COAD	SEC61GP1 →	+0.535	+5.602	<.001	.004	3	1
COAD	MEMO1P3 →	+0.275	+5.357	<.001	.006	3	1
COAD	RN7SL645P →	+0.298	+5.602	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

UBC by PSMD9 expression — UCEC

Explore this box plot interactively →