PSMD3

Across TCGA cell cohorts, PSMD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,445 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMD3-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Positive regulation of mitotic cytokinesis, and Mitotic spindle elongation. Each is linked with PSMD3 in more than 10 cancer types. Because this analysis shows association rather than direction, both PSMD3-to-partner and partner-to-PSMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by PSMD3-low versus PSMD3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD3→partner) and Y-score (partner→PSMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication-dependent chromatin assembly →	+0.119	+0.850	<.001	<.001	3	11
BLOOD_Myeloma	Positive regulation of mitotic cytokinesis →	+0.156	+1.079	<.001	<.001	3	11
BONE	Mitotic spindle elongation →	+0.190	+0.564	.003	<.001	3	11
BONE	Mitotic spindle midzone assembly →	+0.190	+0.564	.003	<.001	3	11
PANCREAS	Nucleosome disassembly →	+0.132	+0.666	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.066	+0.942	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,445 associations by consensus.

DNA replication-dependent chromatin assembly by PSMD3 expression — PANCREAS

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