PSMD3

Across TCGA cell cohorts, PSMD3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMD3-associated genes across cancer lineages are RBP2, INSM2, and PRR23D2. Each is linked with PSMD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD3-to-partner and partner-to-PSMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBP2 grouped by PSMD3-low versus PSMD3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD3→partner) and Y-score (partner→PSMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RBP2 →	+0.042	+4.037	.001	.004	3	1
BLOOD_Leukemia	INSM2 →	+0.163	+3.769	.002	.008	3	1
BLOOD_Leukemia	PRR23D2 →	+0.267	+4.137	<.001	.003	3	1
SKIN	OR1L3 →	+0.019	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RBP2 by PSMD3 expression — BLOOD_Leukemia

Explore this box plot interactively →