PSMD14

Across TCGA patient cohorts, PSMD14 mutation is significantly associated with the RNA expression of many other genes, with 1,254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD14-associated genes across cancer lineages are POLR3KP2, MIR32, and RNA5SP163. Each is linked with PSMD14 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD14-to-partner and partner-to-PSMD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POLR3KP2 grouped by PSMD14-low versus PSMD14-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD14→partner) and Y-score (partner→PSMD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	POLR3KP2 →	+0.431	+6.003	<.001	.002	3	2
UCEC	MIR32 →	+0.245	+2.484	<.001	.007	3	2
UCEC	RNA5SP163 →	+0.133	+3.079	.002	.006	3	2
COAD	OR5D3P →	+0.113	+6.917	<.001	<.001	3	1
COAD	RNU1-65P →	+0.398	+6.917	<.001	<.001	3	1
COAD	MRPL35P1 →	+0.261	+5.017	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,254 associations by consensus.

POLR3KP2 by PSMD14 expression — COAD

Explore this box plot interactively →