Across TCGA patient cohorts, PSMD12 mutation is significantly associated with the RNA expression of many other genes, with 1,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD12-associated genes across cancer lineages are CICP28, MIR6833, and RNU6-502P. Each is linked with PSMD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD12-to-partner and partner-to-PSMD12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD12→partner) and Y-score (partner→PSMD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	CICP28 →	+0.018	+5.108	<.001	.008	3	2
SKCM	MIR6833 →	+0.693	+4.801	<.001	.003	3	2
LUAD	RNU6-502P →	+0.347	+4.631	<.001	.008	3	2
LUAD	RN7SKP247 →	+0.181	+6.108	<.001	.001	3	2
LUAD	RN7SL134P →	+0.197	+5.000	<.001	.002	3	2
LIHC	RNU6ATAC30P →	+0.369	+5.268	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,847 associations by consensus.

Exploration

PSMD12 survival (RNA) · tumor vs normal (RNA) · all PSMD12 data types