Across TCGA cell cohorts, PSMD12 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSMD12-associated genes across cancer lineages are CCDC54, OR2C1, and DNASE1L3. Each is linked with PSMD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD12-to-partner and partner-to-PSMD12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD12→partner) and Y-score (partner→PSMD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC54 →	+0.135	+3.736	<.001	.004	3	1
LARGE_INTESTINE	OR2C1 →	+0.153	+3.725	<.001	.008	3	1
LARGE_INTESTINE	DNASE1L3 →	+0.085	+3.491	.003	.008	2	1
LARGE_INTESTINE	HMX3 →	+0.928	+3.531	<.001	.007	2	1
LARGE_INTESTINE	MYO3A →	+0.729	+3.491	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

PSMD12 survival (RNA) · tumor vs normal (RNA) · all PSMD12 data types