PSMD10

Across TCGA pan-cancer cohorts, PSMD10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PSMD10 data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PSMD10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PSMD10 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where PSMD10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.539	0.834	.005	15	view →
PDAC	OS	Median	IV	0.491	0.836	.024	8	view →
HNSC	DFS	Median	All	0.879	0.686	.002	5	view →
UCEC	DFS	Tertile	III,IV	0.503	1.000	.049	4	view →
LSCC	DFS	Median	II,III,IV	0.444	0.883	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PSMD10–CCRCC (DFS)

Open the CCRCC breakdown →