PSMD10

Across TCGA cell cohorts, PSMD10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,488 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMD10-associated GO terms across cancer lineages are Translation reinitiation, Positive regulation of dopamine metabolic process, and Regulation of DNA damage checkpoint. Each is linked with PSMD10 in more than 11 cancer types. Because this analysis shows association rather than direction, both PSMD10-to-partner and partner-to-PSMD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translation reinitiation grouped by PSMD10-low versus PSMD10-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD10→partner) and Y-score (partner→PSMD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Translation reinitiation →	+0.088	+0.615	<.001	.002	3	12
KIDNEY	Positive regulation of dopamine metabolic process →	+0.133	+0.495	.002	.008	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.101	+0.720	.001	.007	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic cell cycle phase transition →	+0.058	+0.514	<.001	<.001	3	10
OVARY	Mitotic spindle elongation →	+0.219	+0.774	<.001	<.001	3	10
OVARY	Mitotic spindle midzone assembly →	+0.219	+0.774	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,488 associations by consensus.

Translation reinitiation by PSMD10 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →