PSMD1

Across TCGA patient cohorts, PSMD1 mutation is significantly associated with the RNA expression of many other genes, with 2,129 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD1-associated genes across cancer lineages are RNU6ATAC30P, EMID1, and MIR548S. Each is linked with PSMD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSMD1-to-partner and partner-to-PSMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6ATAC30P grouped by PSMD1-low versus PSMD1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD1→partner) and Y-score (partner→PSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6ATAC30P →	+0.218	+3.646	.007	.006	3	3
UCEC	EMID1 →	-1.186	-2.989	<.001	<.001	3	3
COAD	MIR548S →	+0.820	+3.145	<.001	.009	3	3
COAD	RN7SL210P →	+0.373	+3.283	<.001	.007	3	3
SKCM	RPL29P14 →	+0.336	+3.341	.005	.005	3	3
BRCA	RN7SL248P →	+0.067	+4.786	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,129 associations by consensus.

RNU6ATAC30P by PSMD1 expression — BRCA

Explore this box plot interactively →