PSMD1

Across TCGA cell cohorts, PSMD1 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSMD1-associated genes across cancer lineages are OR52L1, S100A7A, and OR10A5. Each is linked with PSMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD1-to-partner and partner-to-PSMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52L1 grouped by PSMD1-low versus PSMD1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD1→partner) and Y-score (partner→PSMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR52L1 →	+0.055	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	S100A7A →	+0.026	+4.643	<.001	.005	3	1
OVARY	OR10A5 →	+0.036	+4.029	<.001	.009	3	1
OVARY	ELSPBP1 →	+0.137	+4.029	.006	.009	3	1
BREAST	OR2AK2 →	+0.215	+4.781	<.001	.003	3	1
BREAST	HIGD1C →	+0.120	+4.672	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

OR52L1 by PSMD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →