PSMC2

Across TCGA patient cohorts, PSMC2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,656 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMC2-associated genes across cancer lineages are PABPC5, KCNA5, and SYNPO2. Each is linked with PSMC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSMC2-to-partner and partner-to-PSMC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMC2 versus PABPC5 in GBM, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC2→partner) and Y-score (partner→PSMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PABPC5 →	-0.836	-0.136	.003	<.001	3	6
CCRCC	KCNA5 →	-0.738	-0.096	.002	.005	3	6
COAD	SYNPO2 →	-1.521	-0.197	<.001	<.001	3	6
COAD	PGM5 →	-1.148	-0.153	.001	.003	3	6
COAD	CAB39L →	-1.178	-0.171	<.001	.002	3	5
COAD	PDE1A →	-0.674	-0.185	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,656 associations by consensus.

PSMC2 vs PABPC5 — GBM

Explore this scatter interactively →