PSMC1P9

Across TCGA pan-cancer cohorts, PSMC1P9 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PSMC1P9 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PSMC1P9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PSMC1P9 expression acts as an unfavorable survival marker, although some lineages such as CESC and THCA show a favorable association.

UVM, ACC, and CESC are the cancer types where PSMC1P9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.207	1.000	.002	48	view →
ACC	DFS	Tertile	II,III,IV	0.171	0.577	<.001	48	view →
CESC	DFS	Median	II,III,IV	0.664	0.302	.007	44	view →
THCA	DFS	Quartile	All	0.960	0.558	.002	37	view →
READ	DFS	Median	III,IV	0.944	0.574	.005	28	view →
STAD	OS	Median	All	0.639	0.729	.015	25	view →
BLCA	DFS	Tertile	III,IV	0.470	0.607	.021	24	view →
MESO	OS	Median	All	0.422	0.648	.004	22	view →
PAAD	OS	Quartile	All	0.230	0.509	.002	21	view →
LUSC	DFS	Median	II,III,IV	0.769	0.640	.011	20	view →
OV	OS	Median	IV	0.747	0.509	.028	16	view →
CHOL	OS	Tertile	II,III,IV	0.322	0.784	.015	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PSMC1P9–UVM (DFS)

Open the UVM breakdown →