PSMC1P5

Across TCGA pan-cancer cohorts, PSMC1P5 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PSMC1P5 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PSMC1P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PSMC1P5 expression acts as an unfavorable survival marker, although some lineages such as UCS and CESC show a favorable association.

UVM, KIRC, and BLCA are the cancer types where PSMC1P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.435	0.787	<.001	108	view →
KIRC	DFS	Tertile	III,IV	0.236	0.558	.005	76	view →
BLCA	OS	Tertile	III,IV	0.225	0.455	.004	36	view →
LUSC	OS	Quartile	III,IV	0.397	0.686	.008	36	view →
SKCM	DFS	Tertile	IV	0.038	0.472	<.001	26	view →
UCS	DFS	Tertile	All	0.659	0.382	.022	26	view →
ACC	DFS	Quartile	All	0.115	0.652	<.001	25	view →
UCEC	DFS	Tertile	All	0.861	0.909	.007	14	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	12	view →
KICH	DFS	Quartile	II,III,IV	0.409	0.827	.009	11	view →
CESC	OS	Median	All	0.909	0.837	.031	10	view →
STAD	DFS	Tertile	All	0.605	0.727	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PSMC1P5–UVM (DFS)

Open the UVM breakdown →